FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CG8839KO
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General Information
Symbol
Dmel\CG8839KO
Species
D. melanogaster
Name
FlyBase ID
FBal0361663
Feature type
allele
Associated gene
Dmel\CG8839
Associated Insertion(s)
TI{TI}CG8839KO
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Jacobs and Sehgal, 2020)
Mutagen
CRISPR/Cas9
(Jacobs and Sehgal, 2020)
gene targeting by homologous recombination
(Jacobs and Sehgal, 2020)
Progenitor genotype
Associated Insertion(s)
TI{TI}CG8839KO
Cytology
Description

The coding region of the endogenous CG8839 locus has been deleted and replaced by a sequence cassette that contains a Disc\RFPDsRed(T1).3xP3.cHa marker flanked by loxP sites and a single attP site

(Jacobs and Sehgal, 2020)
Allele components
Component
Use(s)
Also carries
attP
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  epilepsy
      modeled by eas2
      (Jacobs and Sehgal, 2020)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      CG8839KO
      (Jacobs and Sehgal, 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)