FB2026_03 , released September 17, 2026
Allele: Dmel\tinmDPE
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General Information
Symbol
Dmel\tinmDPE
Species
D. melanogaster
Name
FlyBase ID
FBal0362044
Feature type
allele
Associated gene
Dmel\tin
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Levi et al., 2020)
Mutagen
CRISPR/Cas9
(Levi et al., 2020)
gene targeting by homologous recombination
(Levi et al., 2020)
Progenitor genotype
Cytology
Description

Mutation (AGACACG to CTCATGT) within a regulatory motif of the tin promoter. This results in a reduction in levels of tin RNA.

(Levi et al., 2020)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
MNV
3R:21,379,006..21,379,012 [+]
Nucleotide change:

AGACACG21379006CTCATGT

Reported nucleotide change:

AGACACG>CTCATGT

Comment:

Mutation of 7bp in the downstream core promoter element, DPE, of tin.

(Levi et al., 2020)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      tinmDPE
      (Levi et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)