FlyBase Allele Report: Dmel\cic[SSTS-A.UAS]

General Information

Symbol

Dmel\cic^SSTS-A.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0363556

Feature type

allele

Associated gene

Dmel\cic

Associated Insertion(s)

Carried in Construct

P{UAS-cic.SSTS-A}

Key Links

Transgenic product class

missense_variant

(Yang et al., 2016)

polypeptide_post_translational_processing_variant

(Yang et al., 2016)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Yang et al., 2016)

polypeptide_post_translational_processing_variant

(Yang et al., 2016)

Mutagen

in vitro construct

(Yang et al., 2016)

Progenitor genotype

Carried in construct

P{UAS-cic.SSTS-A}

Cytology

Description

UAS regulatory sequences drive expression of cic in which four amino acids that have been found to be phosphorylated by mnb have been mutated to a non-phosphorylatable Ala residue (amino acid substitutions S41A, S49A, T89A and S91A).

(Yang et al., 2016)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

cic

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage, with Scer\GAL4^Bx-MS1096

(Yang et al., 2016)

visible | adult stage, with Scer\GAL4^Bx-MS1096

(Yang et al., 2016)

Phenotype Manifest In

wing, with Scer\GAL4^Bx-MS1096

(Yang et al., 2016)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^Bx-MS1096, cic^SSTS-A.UAS has visible | adult stage phenotype, non-enhanceable by mnb^UAS.cYa/Scer\GAL4^Bx-MS1096

(Yang et al., 2016)

Scer\GAL4^Bx-MS1096, cic^SSTS-A.UAS has decreased size | adult stage phenotype, non-enhanceable by mnb^UAS.cYa/Scer\GAL4^Bx-MS1096

(Yang et al., 2016)

NOT suppressed by

Statement

Reference

Scer\GAL4^Bx-MS1096, cic^SSTS-A.UAS has visible | adult stage phenotype, non-suppressible by mnb^UAS.cYa/Scer\GAL4^Bx-MS1096

(Yang et al., 2016)

Scer\GAL4^Bx-MS1096, cic^SSTS-A.UAS has decreased size | adult stage phenotype, non-suppressible by mnb^UAS.cYa/Scer\GAL4^Bx-MS1096

(Yang et al., 2016)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^Bx-MS1096, cic^SSTS-A.UAS has wing phenotype, non-enhanceable by mnb^UAS.cYa/Scer\GAL4^Bx-MS1096

(Yang et al., 2016)

NOT suppressed by

Statement

Reference

Scer\GAL4^Bx-MS1096, cic^SSTS-A.UAS has wing phenotype, non-suppressible by mnb^UAS.cYa/Scer\GAL4^Bx-MS1096

(Yang et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

cic^SSTS-A.UAS

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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