FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: TEV\NIa3xmut.RSRT.Flp1.LexAop2.Tag:M(rCd2),Tag:MYC
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General Information
Symbol
TEV\NIa3xmut.RSRT.Flp1.LexAop2.Tag:M(rCd2),Tag:MYC
Species
P. Tobacco etch virus
Name
FlyBase ID
FBal0365170
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Transgenic product class
Nature of the Allele
Transgenic product class
Cytology
Description

lexAop (LexAop2) regulatory sequences are fused upstream of a removable cassette comprised of FLPD5 and Hsp70b and SV40 3' UTRs surrounded by RSRT recombination sites. Downstream of the removable cassette is a coding sequence encoding TEVp(3xmut) plus a transmembrane sequence (Tag:M(rCd2)) that targets TEVp(3xmut) to the cell surface. The N-terminus of the coding sequence has the C. elegans PAT3 signal peptide sequence for endoplasmic reticulum targeting, while the C-terminus has the Kir2.1 ER export signal to improve trafficking to the plasma membrane, followed by the P10 3' UTR. Tag:MYC has been introduced in between the TEVp(3xmut) and Tag:M(rCd2) sequence. Removal of the cassette allows the TEVp(3xmut)-Tag:M(rCd2) protein to be expressed under control of lexAop. (GenBank MN658789.) Used in the first (release) step of the BacTrace system.

Allele components
Component
Use(s)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
TEV\NIa3xmut.RSRT.Flp1.LexAop2.Tag:M(rCd2),Tag:MYC
Name Synonyms
Secondary FlyBase IDs
    References (1)