FlyBase Allele Report: Hsap\NFIA[WT.UAS]

General Information

Symbol

Hsap\NFIA^WT.UAS

Species

H. sapiens

Name

FlyBase ID

FBal0368838

Feature type

allele

Associated gene

Hsap\NFIA

Associated Insertion(s)

Carried in Construct

P{UAS-hNFIA.WT}

Key Links

Transgenic product class

cDNA

(Uehara et al., 2021)

wild_type

(Uehara et al., 2021)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Uehara et al., 2021)

wild_type

(Uehara et al., 2021)

Mutagen

in vitro construct

(Uehara et al., 2021)

Progenitor genotype

Carried in construct

P{UAS-hNFIA.WT}

Cytology

Description

UAS regulates expression of wild type Hsap\NFIA cDNA.

(Uehara et al., 2021)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Hsap\NFIA

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

homeotic | adult stage, with Scer\GAL4^ey.PH

(Uehara et al., 2021)

lethal - all die before end of first instar larval stage, with Scer\GAL4^nSyb.PP

(Uehara et al., 2021)

some die during embryonic stage, with Scer\GAL4^nSyb.PP

(Uehara et al., 2021)

some die during first instar larval stage, with Scer\GAL4^nSyb.PP

(Uehara et al., 2021)

visible | adult stage, with Scer\GAL4^ey.PH

(Uehara et al., 2021)

Phenotype Manifest In

antenna | decreased number, with Scer\GAL4^GMR.PF

(Uehara et al., 2021)

eye, with Scer\GAL4^GMR.PF

(Uehara et al., 2021)

leg | ectopic, with Scer\GAL4^GMR.PF

(Uehara et al., 2021)

Detailed Description

Statement

Reference

The expression of Hsap\NFIA^WT.UAS under the control of Scer\GAL4^GMR.PF induces a rough eye phenotype. Expression under the control of Scer\GAL4^ey.PH causes a antenna-to-leg transformation.

(Uehara et al., 2021)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Hsap\NFIA^WT.UAS

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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