FB2026_02 , released June 18, 2026
Allele: Dmel\l(2)eflHR
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General Information
Symbol
Dmel\l(2)eflHR
Species
D. melanogaster
Name
FlyBase ID
FBal0369127
Feature type
allele
Associated gene
Dmel\l(2)efl
Associated Insertion(s)
TI{TI}l(2)eflHR
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Bertin et al., 2021)
gene targeting by homologous recombination
(Bertin et al., 2021)
Progenitor genotype
Associated Insertion(s)
TI{TI}l(2)eflHR
Cytology
Description

Most of the l(2)efl coding sequence has been deleted. It has been replaced by sequence encoding a loxP cassette that contains a Disc\RFPDsRed(T1).3xP3.cHa marker.

(Bertin et al., 2021)
Allele components
Component
Use(s)
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      l(2)eflHR/l(2)eflHR stage 15 embryos show irregular growth of lateral transverse (LT) muscles, dissociation between LT1 and LT2 and/or between LT2 and LT3, irregular LT shape and branched LT extremities, and reduction in the number of LTs.

      (Bertin et al., 2021)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dCryABHR
      (Bertin et al., 2021)
      l(2)eflHR
      Name Synonyms
      Secondary FlyBase IDs
        References (1)