FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Gel9.3
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General Information
Symbol
Dmel\Gel9.3
Species
D. melanogaster
Name
FlyBase ID
FBal0369128
Feature type
allele
Associated gene
Dmel\Gel
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Bertin et al., 2021)
Progenitor genotype
Cytology
Description

2bp insertion in the 5' region of the Gel coding sequence; results in a premature stop codon.

(Bertin et al., 2021)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Gel9.3/Gel9.3 stage 15 embryos show lateral transverse (LT) muscle defects, including irregular growth and enlarged fibers, muscle dissociation, and muscle splitting, with asynchronous growth and sub-division into two fibers, leading to increased number of muscles; these muscles also show disrupted sarcomeric patterns.. In stage 16, these muscles show increased number of nuclei. Gel9.3/Gel9.3 stage 15 embryos also show a decrease in SBM and LO1 muscles.

      Gel9.3/Gel9.8 stage 15 embryos show lateral transverse (LT) muscle splitting.

      (Bertin et al., 2021)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Gel9.3
      (Bertin et al., 2021)
      Gel9.3
      Name Synonyms
      Secondary FlyBase IDs
        References (1)