FB2026_03 , released September 17, 2026
Allele: Dmel\twyNPΔ25
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General Information
Symbol
Dmel\twyNPΔ25
Species
D. melanogaster
Name
FlyBase ID
FBal0369327
Feature type
allele
Associated gene
Dmel\twy
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Hodge et al., 2021)
Mutagen
P-element activity
(Hodge et al., 2021)
Progenitor genotype
P{GawB}Pi3K68DNP2686
(Hodge et al., 2021)
Cytology
Description

Imprecise excision of P{GawB}Pi3K68DNP2686 resulting in a deletion of the 3' end of twy.

(Hodge et al., 2021)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      twyNPΔ25/twyNPΔ25, twyNPΔ25/Df(3L)BSC727 adults are uncoordinated and fail to show climbing ability. Testis appear fragile.

      Larvae show decreased crawling speed, only covering short distances, frequently pausing and curling into a ball or adopting a 'C'-shape rather than changing direction; these larvae show decreased touch response.

      (Hodge et al., 2021)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      twyNPΔ25 is rescued by twy+tgR1

      (Hodge et al., 2021)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      twyNPΔ25
      (Hodge et al., 2021)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)