FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rtel1xp409
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General Information
Symbol
Dmel\Rtel1xp409
Species
D. melanogaster
Name
FlyBase ID
FBal0370211
Feature type
allele
Associated gene
Dmel\Rtel1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Yang et al., 2021)
Progenitor genotype
Cytology
Description

Amino acid replacement: K183term.

(Yang et al., 2021)

An A to T conversion at nucleotide base 547 of the CDS, leading to a premature stop codon in the conserved N-terminal DEAD2 domain.

(Yang et al., 2021)

Nucleotide substitution: A547T.

(Yang et al., 2021)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
X:5,748,415..5,748,415 [+]
Nucleotide change:

A5748415T

Reported nucleotide change:

A547T

Amino acid change:

K183term | Rtel1-PA; K183term | Rtel1-PB

Reported amino acid change:

K183term

(Yang et al., 2021)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      Rtel1xp409 has decreased cell number | larval stage | progressive phenotype, suppressible | partially by lokp6

      (Yang et al., 2021)
      NOT suppressed by
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Rtel1xp409 has male germline stem cell | larval stage | decreased number phenotype, suppressible | partially by lokp6

      (Yang et al., 2021)
      NOT suppressed by
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Rtel1xp409 is rescued by Rtel1fTRG01096.sfGFP-TVPTBF

      (Yang et al., 2021)
      Partially rescued by

      Rtel1xp409 is partially rescued by Rtel1UAS.Tag:FLAG/Scer\GAL4tj.PU

      (Yang et al., 2021)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Rtel1xp409
      xp409
      (Yang et al., 2021)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)