FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Hsap\HIPK2UAS.Tag:MYC
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General Information
Symbol
Hsap\HIPK2UAS.Tag:MYC
Species
H. sapiens
Name
FlyBase ID
FBal0371181
Feature type
allele
Associated gene
Hsap\HIPK2
Associated Insertion(s)
Carried in Construct
P{UAS-hHIPK2.MYC}
Key Links
Transgenic product class
cDNA
(Kinsey et al., 2021)
wild_type
(Kinsey et al., 2021)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Kinsey et al., 2021)
wild_type
(Kinsey et al., 2021)
Mutagen
in vitro construct
(Kinsey et al., 2021)
Progenitor genotype
Carried in construct
P{UAS-hHIPK2.MYC}
Cytology
Description

UASt regulatory sequences drive expression of Hsap\HIPK2 isoform 1 cDNA. Tagged at the N-terminal with Tag:MYC.

(Kinsey et al., 2021)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\HIPK2
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of Hsap\HIPK2UAS.Tag:MYC under the control of Scer\GAL4dpp.blk1 causes wing abnormalities in the distal central region of the wing blade, with altered pigmentation, as well as ectopic small hairs and sensory bristles resembling those found on halteres.

      Wing disc clonal expression of Hsap\HIPK2UAS.Tag:MYC under the control of Scer\GAL4Act5C.PI leads to increased eye disc size, which is becomes highly distorted.

      (Kinsey et al., 2021)
      External Data
      Interactions
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Hsap\HIPK2UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)