FB2026_02 , released June 18, 2026
Allele: Dmel\Set8RGHL
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General Information
Symbol
Dmel\Set8RGHL
Species
D. melanogaster
Name
FlyBase ID
FBal0375489
Feature type
allele
Associated gene
Dmel\Set8
Associated Insertion(s)
Carried in Construct
PBac{Set8.RGHL}
Key Links
Transgenic product class
missense_variant
(Crain et al., 2022)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Crain et al., 2022)
Mutagen
in vitro construct
(Crain et al., 2022)
Progenitor genotype
Carried in construct
PBac{Set8.RGHL}
Cytology
Description

5493bp genomic fragment that encompasses Set8. Amino acid replacements R634G and H638L have been introduced into the coding sequence.

(Crain et al., 2022)
Allele components
Component
Use(s)
Regulatory region(s)
Set8
Encoded product / tool
Set8
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      FBal0375489:, Set820 is partially rescued by Set8RGHL/Set8RGHL

      (Crain et al., 2022)
      Partially rescues

      Set8RGHL/Set8RGHL partially rescues FBal0375489:, Set820

      (Crain et al., 2022)
      Fails to rescue

      Set8RGHL fails to rescue Set820

      (Crain et al., 2022)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Set8RGHL
      (Crain et al., 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)