FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\enNK14
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General Information
Symbol
Dmel\enNK14
Species
D. melanogaster
Name
FlyBase ID
FBal0375964
Feature type
allele
Associated gene
Dmel\en
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Kato et al., 2022)
Progenitor genotype
Cytology
Description

A deletion of 15 nt in the first exon, predicted to replace six contiguous amino acids, Ser340-Ala345, with one Thr. This deletion is located within a serine-rich region, in which Ser325, Ser340 and Thr341 have been suggested as targets of Protein Kinase C.

(Kato et al., 2022)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:11,526,638..11,526,652 [-]
Comment:

A 15bp deletion that replaces 6 amino acids (Ser340-Ala345) with one Thr. This was one of 23 nucleotide substitutions and 32 indels in the en region in the mutant. The others do not alter the amino acid sequence.

(Kato and Itoh, 2022.9.8, Kato et al., 2022)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      enNK14
      (Kato et al., 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)