FlyBase Allele Report: Hsap\F8A1[UAS.cXa]

General Information

Symbol

Hsap\F8A1^UAS.cXa

Species

H. sapiens

Name

UAS construct a of Xu

FlyBase ID

FBal0376311

Feature type

allele

Associated gene

Hsap\F8A1

Associated Insertion(s)

Carried in Construct

P{UAS-hF8A1.X}

Key Links

Transgenic product class

cDNA

(Xu et al., 2022)

wild_type

(Xu et al., 2022)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Xu et al., 2022)

wild_type

(Xu et al., 2022)

Mutagen

in vitro construct

(Xu et al., 2022)

Progenitor genotype

Carried in construct

P{UAS-hF8A1.X}

Cytology

Description

UASt regulates expression of a Hsap\F8A1 full-length cDNA.

(Xu et al., 2022)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Hsap\F8A1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Hsap\F8A1^UAS.cXa, Scer\GAL4^nSyb.PS is an enhancer of decreased cell number | adult stage phenotype of Hsap\HTT^128Q.FL.UAS, Scer\GAL4^nSyb.PS

(Xu et al., 2022)

Hsap\F8A1^UAS.cXa, Scer\GAL4^nSyb.PS is an enhancer of abnormal neuroanatomy | adult stage phenotype of Hsap\HTT^128Q.FL.UAS, Scer\GAL4^nSyb.PS

(Xu et al., 2022)

Hsap\F8A1^UAS.cXa, Scer\GAL4^GMR.PU is an enhancer of decreased cell number | adult stage phenotype of Hsap\HTT^{145Q.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Xu et al., 2022)

Hsap\F8A1^UAS.cXa, Scer\GAL4^GMR.PU is an enhancer of abnormal neuroanatomy | adult stage phenotype of Hsap\HTT^{145Q.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Xu et al., 2022)

NOT Enhancer of

Statement

Reference

Hsap\F8A1^UAS.cXa, Scer\GAL4^nSyb.PS is a non-enhancer of short lived phenotype of Hsap\HTT^128Q.FL.UAS, Scer\GAL4^nSyb.PS

(Xu et al., 2022)

Suppressor of

Statement

Reference

Hsap\F8A1^UAS.cXa/Scer\GAL4^da.G32 is a suppressor of short lived phenotype of Hap40^ko3

(Xu et al., 2022)

NOT Suppressor of

Statement

Reference

Hsap\F8A1^UAS.cXa, Scer\GAL4^nSyb.PS is a non-suppressor of short lived phenotype of Hsap\HTT^128Q.FL.UAS, Scer\GAL4^nSyb.PS

(Xu et al., 2022)

Phenotype Manifest In

Enhancer of

Statement

Reference

Hsap\F8A1^UAS.cXa, Scer\GAL4^nSyb.PS is an enhancer of eye photoreceptor cell | adult stage | decreased number phenotype of Hsap\HTT^128Q.FL.UAS, Scer\GAL4^nSyb.PS

(Xu et al., 2022)

Hsap\F8A1^UAS.cXa, Scer\GAL4^GMR.PU is an enhancer of eye photoreceptor cell | adult stage | decreased number phenotype of Hsap\HTT^{145Q.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Xu et al., 2022)

Hsap\F8A1^UAS.cXa, Scer\GAL4^GMR.PU is an enhancer of ommatidium | adult stage phenotype of Hsap\HTT^{145Q.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Xu et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Hsap\F8A1^UAS.cXa

Name Synonyms

UAS construct a of Xu

Secondary FlyBase IDs

References (1)

Report Sections

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