FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\RpL12K3A
Open Close
General Information
Symbol
Dmel\RpL12K3A
Species
D. melanogaster
Name
FlyBase ID
FBal0376576
Feature type
allele
Associated gene
Dmel\RpL12
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Grunchec et al., 2022)
Progenitor genotype
Cytology
Description

Amino acid replacement: K3A.

(Grunchec et al., 2022)

Replacement of the lysine 3 codon with a alanine codon, which is not subject to methylation and does not interact with the chromodomain of the corto protein.

(Grunchec et al., 2022)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
MNV
2R:24,060,547..24,060,549 [+]
Nucleotide change:

AAA24060547GCC

Amino acid change:

K4A | RpL12-PA; K4A | RpL12-PB; K4A | RpL12-PC

Reported amino acid change:

K3A

Comment:

Codon K4 (third codon after ATG) of RpL12 changed to A (AAA to GCC).

(Grunchec et al., 2022)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      RpL12K3A
      uL11K3A
      (Grunchec et al., 2022)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)