FlyBase Allele Report: Dmel\Cph[1]

General Information

Symbol

Dmel\Cph¹

Species

D. melanogaster

Name

FlyBase ID

FBal0376749

Feature type

allele

Associated gene

Dmel\Cph

Associated Insertion(s)

P+PBac{XP3.WH3}Cph¹

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

FLPase

Nature of the Allele

Allele class

Mutagen

FLPase

(Fox et al., 2022)

Progenitor genotype

PBac{WH}f06617

(Fox et al., 2022)

P{XP}Cph^d03295

(Fox et al., 2022)

Associated Insertion(s)

P+PBac{XP3.WH3}Cph¹

Cytology

Description

Deletion of 46kb of genomic sequence, within which Cph is the only annotated gene (FlyBase release 6).

(Fox et al., 2022)

Allele components

Component

Use(s)

Inserted element

P+PBac{XP3.WH3}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Also carries

FRT

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

X:7,195,692..7,241,777 [+]

(Fox et al., 2022)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell number | embryonic stage

(Fox et al., 2022)

lethal - all die during embryonic stage

(Fox et al., 2022)

Phenotype Manifest In

larval DA3 motor neuron | embryonic stage | increased number

(Fox et al., 2022)

U neuron | embryonic stage | increased number

(Fox et al., 2022)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Cph¹ has increased cell number | embryonic stage phenotype, non-enhanceable by cas²⁴

(Fox et al., 2022)

Suppressed by

Statement

Reference

Cph¹ has increased cell number | embryonic stage phenotype, suppressible by Scer\GAL4^en-e16E/cas^UAS.cKa

(Fox et al., 2022)

NOT suppressed by

Statement

Reference

Cph¹ has increased cell number | embryonic stage phenotype, non-suppressible by cas²⁴

(Fox et al., 2022)

NOT Enhancer of

Statement

Reference

Cph¹ is a non-enhancer of increased cell number | embryonic stage phenotype of cas²⁴

(Fox et al., 2022)

NOT Suppressor of

Statement

Reference

Cph¹ is a non-suppressor of increased cell number | embryonic stage phenotype of cas²⁴

(Fox et al., 2022)

Other

Statement

Reference

Cph¹, Kr^UAS.cHa, Scer\GAL4^en-e16E has increased cell number | embryonic stage phenotype

(Fox et al., 2022)

Cph¹, Scer\GAL4^ase.PZ, hb^UAS.cWa has increased cell number | embryonic stage phenotype

(Fox et al., 2022)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Cph¹ has U neuron | embryonic stage | increased number phenotype, non-enhanceable by cas²⁴

(Fox et al., 2022)

Suppressed by

Statement

Reference

Cph¹ has U neuron | increased number | embryonic stage phenotype, suppressible by Scer\GAL4^en-e16E/cas^UAS.cKa

(Fox et al., 2022)

NOT suppressed by

Statement

Reference

Cph¹ has U neuron | increased number | embryonic stage phenotype, non-suppressible by cas²⁴

(Fox et al., 2022)

NOT Enhancer of

Statement

Reference

Cph¹ is a non-enhancer of U neuron | embryonic stage | increased number phenotype of cas²⁴

(Fox et al., 2022)

NOT Suppressor of

Statement

Reference

Cph¹ is a non-suppressor of U neuron | increased number | embryonic stage phenotype of cas²⁴

(Fox et al., 2022)

Other

Statement

Reference

Cph¹, Kr^UAS.cHa, Scer\GAL4^en-e16E has larval DA2 motor neuron | increased number | embryonic stage phenotype

(Fox et al., 2022)

Cph¹, Scer\GAL4^ase.PZ, hb^UAS.cWa has U neuron | increased number | embryonic stage phenotype

(Fox et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Cph¹ is rescued by Cph^UAS.RL/Scer\GAL4^wor.PA

(Fox et al., 2022)

Not rescued by

Cph¹ is not rescued by Scer\GAL4^elav-C155/Cph^UAS.RL

(Fox et al., 2022)

Cph¹ is not rescued by Cph^UAS.RL/Scer\GAL4^ase.PZ

(Fox et al., 2022)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Cph¹

cph¹

(Fox et al., 2022)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close