Mutation that specifically affects the p53 B isoform. Three deletions are present; one results in a frameshift plus a premature stop codon after only 5 amino acid residues, another deletes a splice donor site.
First of three small closely spaced deletions just after the ATG of p53-RA. The second leads to a frameshift and early translation termination after 5 amino acids and the third removes a splice donor site.
Second of three small closely spaced deletions just after the ATG of p53-RA. The second leads to a frameshift and early translation termination after 5 amino acids and the third removes a splice donor site.
Third of three small closely spaced deletions just after the ATG of p53-RA. The second leads to a frameshift and early translation termination after 5 amino acids and the third removes a splice donor site.
