FlyBase Allele Report: Dmel\Wdr59[1]

General Information

Symbol

Dmel\Wdr59¹

Species

D. melanogaster

Name

FlyBase ID

FBal0387353

Feature type

allele

Associated gene

Dmel\Wdr59

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

amorphic allele - molecular evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Zhang et al., 2023)

Mutagen

P-element activity

(Zhang et al., 2023)

Progenitor genotype

P{EP}Wdr59^G7958

(Zhang et al., 2023)

Cytology

Description

Imprecise excision of P{EP}Wdr59^G7958 results in a 2845bp deletion ( 2L:11091633..11094477 ) in Wdr59.

(Zhang et al., 2023)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

2L:11,091,633..11,094,477 [+]

Comment:

A 2845bp deletion resulting from the imprecise excision of P{EP}Wdr59^G7958 removes most of Wdr59.

(Zhang et al., 2023)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile

(Zhang et al., 2023)

increased size | oogenesis

(Zhang et al., 2023)

viable

(Zhang et al., 2023)

Phenotype Manifest In

egg chamber | germline clone

(Zhang et al., 2023)

ovary

(Zhang et al., 2023)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Wdr59¹ has increased size | germline clone | oogenesis phenotype, suppressible by mio^ko2/mio^ko2

(Zhang et al., 2023)

Wdr59¹ has increased size | germline clone | oogenesis phenotype, suppressible by Nup44A^Δ15/Nup44A^Δ15

(Zhang et al., 2023)

NOT Suppressor of

Statement

Reference

Wdr59¹ is a non-suppressor of decreased size | oogenesis phenotype of mio^ko2

(Zhang et al., 2023)

Wdr59¹ is a non-suppressor of decreased size | oogenesis phenotype of Nup44A^Δ15

(Zhang et al., 2023)

Phenotype Manifest In

Suppressed by

Statement

Reference

Wdr59¹ has egg chamber | germline clone phenotype, suppressible by mio^ko2/mio^ko2

(Zhang et al., 2023)

Wdr59¹ has egg chamber | germline clone phenotype, suppressible by Nup44A^Δ15/Nup44A^Δ15

(Zhang et al., 2023)

NOT Suppressor of

Statement

Reference

Wdr59¹ is a non-suppressor of ovary phenotype of mio^ko2

(Zhang et al., 2023)

Wdr59¹ is a non-suppressor of ovary phenotype of Nup44A^Δ15

(Zhang et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Wdr59¹ is rescued by Wdr59^{+tCH321-87J17}

(Zhang et al., 2023)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Wdr59¹

wdr59¹

(Zhang et al., 2023)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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