FB2026_03 , released September 17, 2026
Allele: Dmel\GluClαV263I
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General Information
Symbol
Dmel\GluClαV263I
Species
D. melanogaster
Name
FlyBase ID
FBal0388737
Feature type
allele
Associated gene
Dmel\GluClα
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Sun et al., 2023)
gene targeting by homologous recombination
(Sun et al., 2023)
Progenitor genotype
Cytology
Description

Amino acid replacement: V263I.

(Sun et al., 2023)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
MNV
3R:19,763,693..19,763,695 [+]
Nucleotide change:

GTA19763693ATT

Reported nucleotide change:

GTA?ATT

Amino acid change:

V183I | GluClalpha-PE; V261I | GluClalpha-PF; V261I | GluClalpha-PH; V261I | GluClalpha-PI; V262I | GluClalpha-PJ; V261I | GluClalpha-PK; V262I | GluClalpha-PL; V261I | GluClalpha-PM; V261I | GluClalpha-PN; V261I | GluClalpha-PO; V261I | GluClalpha-PP

Reported amino acid change:

V263I

Comment:

The mutation is dubbed V263I after the analagous mutation in P. xylostella, however the mutation is V261I in most D. melanogaster GluClalpha isoforms.

(Sun et al., 2023)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
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      Human Disease Associations
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      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
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      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      GluClαV263I
      Name Synonyms
      Secondary FlyBase IDs
        References (1)