FlyBase Allele Report: Dmel\CG12744[RNAi.UAS.cUa]

General Information

Symbol

Dmel\CG12744^RNAi.UAS.cUa

Species

D. melanogaster

Name

FlyBase ID

FBal0390361

Feature type

allele

Associated gene

Dmel\CG12744

Associated Insertion(s)

Carried in Construct

P{UAS-CG12744.RNAi.U}

Also Known As

UAS-CG12744^RNAi

Key Links

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-CG12744.RNAi.U}

Cytology

Description

UAS regulates expression of an RNAi construct targeting CG12744.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

CG12744

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell number | adult stage, with Scer\GAL4^{Delta-05151-G}

(Wang et al., 2024)

abnormal cell number | adult stage, with Scer\GAL4^NP7397

(Wang et al., 2024, Liu and Jin, 2017)

abnormal cell number | adult stage, with Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

abnormal cell number | adult stage, with Scer\GAL4^{Su(H).GBE.cUa}

(Liu and Jin, 2017)

abnormal cell number | adult stage, with Scer\GAL4^Su(H).GBE

(Wang et al., 2024)

abnormal cell shape | adult stage | conditional, with Scer\GAL4^NP0001

(Liu and Jin, 2017)

abnormal immune response | adult stage, with Scer\GAL4^NP0001

(Liu and Jin, 2017)

abnormal immune response | adult stage, with Scer\GAL4^NP3084

(Liu and Jin, 2017)

abnormal immune response | adult stage, with Scer\GAL4^NP7397

(Liu and Jin, 2017)

chemical sensitive | adult stage, with Scer\GAL4^NP3084

(Liu and Jin, 2017)

decreased occurrence of cell division | adult stage, with Scer\GAL4^Su(H).GBE

(Wang et al., 2024)

increased cell death | adult stage, with Scer\GAL4^NP0001

(Liu and Jin, 2017)

increased cell number | adult stage, with Scer\GAL4^da.PU

(Liu and Jin, 2017)

increased cell number | adult stage, with Scer\GAL4^NP3084

(Liu and Jin, 2017)

increased cell number | adult stage | somatic clone, with Scer\GAL4^Act.PU

(Liu and Jin, 2017)

increased mortality | conditional, with Scer\GAL4^NP0001

(Liu and Jin, 2017)

increased mortality | conditional, with Scer\GAL4^NP3084

(Liu and Jin, 2017)

increased mortality | conditional, with Scer\GAL4^NP7397

(Liu and Jin, 2017)

increased occurrence of cell division | adult stage, with Scer\GAL4^{Delta-05151-G}

(Wang et al., 2024)

increased occurrence of cell division | adult stage, with Scer\GAL4^NP7397

(Wang et al., 2024)

increased occurrence of cell division | adult stage, with Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

Phenotype Manifest In

adult enteroendocrine cell | increased number, with Scer\GAL4^{Delta-05151-G}

(Wang et al., 2024)

adult enteroendocrine cell | increased number, with Scer\GAL4^NP7397

(Wang et al., 2024)

adult enteroendocrine cell | increased number, with Scer\GAL4^Su(H).GBE

(Wang et al., 2024)

adult gut, with Scer\GAL4^da.PU

(Liu and Jin, 2017)

adult gut, with Scer\GAL4^NP3084

(Liu and Jin, 2017)

adult gut, with Scer\GAL4^NP7397

(Wang et al., 2024, Liu and Jin, 2017)

adult gut, with Scer\GAL4^{Su(H).GBE.cUa}

(Liu and Jin, 2017)

adult gut | somatic clone, with Scer\GAL4^Act.PU

(Liu and Jin, 2017)

adult midgut, with Scer\GAL4^NP0001

(Liu and Jin, 2017)

adult midgut epithelial cell, with Scer\GAL4^{Delta-05151-G}

(Wang et al., 2024)

adult midgut epithelial cell, with Scer\GAL4^NP7397

(Wang et al., 2024)

adult midgut epithelial cell, with Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

adult midgut epithelial cell, with Scer\GAL4^Su(H).GBE

(Wang et al., 2024)

adult midgut epithelial cell | conditional, with Scer\GAL4^NP0001

(Liu and Jin, 2017)

nucleus | adult stage, with Scer\GAL4^NP0001

(Liu and Jin, 2017)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

CG12744^RNAi.UAS.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE has abnormal cell number | adult stage phenotype, suppressible by bsk^DN.UAS, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

CG12744^RNAi.UAS.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE has increased occurrence of cell division | adult stage phenotype, suppressible by bsk^DN.UAS, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

CG12744^RNAi.UAS.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE has increased occurrence of cell division | adult stage phenotype, suppressible by tkv^RNAi.UAS.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

CG12744^RNAi.UAS.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE has abnormal cell number | adult stage phenotype, suppressible by Egfr^DN.cUa.UAS, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

CG12744^RNAi.UAS.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE has increased occurrence of cell division | adult stage phenotype, suppressible by Egfr^DN.cUa.UAS, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

CG12744^RNAi.UAS.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE has abnormal cell number | adult stage phenotype, suppressible by tkv^RNAi.UAS.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

CG12744^RNAi.UAS.cUa, Scer\GAL4^NP7397 has abnormal cell number | adult stage phenotype, suppressible by N^ICN.UAS, Scer\GAL4^NP7397

(Liu and Jin, 2017)

CG12744^RNAi.UAS.cUa, Scer\GAL4^NP7397 has abnormal cell number | adult stage phenotype, suppressible by hep^Act.UAS, Scer\GAL4^NP7397

(Liu and Jin, 2017)

Phenotype Manifest In

Suppressed by

Statement

Reference

CG12744^RNAi.UAS.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE has adult midgut epithelial cell phenotype, suppressible by Egfr^DN.cUa.UAS, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

CG12744^RNAi.UAS.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE has adult midgut epithelial cell phenotype, suppressible by bsk^DN.UAS, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

CG12744^RNAi.UAS.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE has adult midgut epithelial cell phenotype, suppressible by tkv^RNAi.UAS.cUa, Scer\GAL4^NP7397, Scer\GAL80^Su(H).GBE

(Wang et al., 2024)

CG12744^RNAi.UAS.cUa, Scer\GAL4^NP7397 has adult gut phenotype, suppressible by hep^Act.UAS, Scer\GAL4^NP7397

(Liu and Jin, 2017)

CG12744^RNAi.UAS.cUa, Scer\GAL4^NP7397 has adult gut phenotype, suppressible by N^ICN.UAS, Scer\GAL4^NP7397

(Liu and Jin, 2017)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

CG12744^RNAi.UAS.cUa is rescued by Scer\GAL4^NP7397/CG12744^UAS.cLa

(Wang et al., 2024)

CG12744^RNAi.UAS.cUa is rescued by Scer\GAL4^NP7397/CG12744^UAS.cLa

(Liu and Jin, 2017)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG12744^RNAi.UAS.cUa

CG12744^VDRC.cUa

Name Synonyms

Secondary FlyBase IDs

References (3)

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