FlyBase Allele Report: Dmel\HDAC4[UAS.Tag:MYC]

General Information

Symbol

Dmel\HDAC4^UAS.Tag:MYC

Species

D. melanogaster

Name

FlyBase ID

FBal0391402

Feature type

allele

Associated gene

Dmel\HDAC4

Associated Insertion(s)

Carried in Construct

P{UAS-HDAC4.Myc}

Key Links

Transgenic product class

wild_type

(Schwartz et al., 2023)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Schwartz et al., 2023)

Mutagen

in vitro construct

(Schwartz et al., 2023)

Progenitor genotype

Carried in construct

P{UAS-HDAC4.Myc}

Cytology

Description

UASt regulatory sequences drive expression of HDAC4 that is tagged at the C-terminal end with 6xTag:MYC.

(Schwartz et al., 2023)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

HDAC4

Tagged with

Tag:MYC

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | adult stage, with Scer\GAL4^elav-C155

(Tan et al., 2024)

abnormal neuroanatomy | adult stage, with Scer\GAL4^ey-OK107

(Tan et al., 2024)

visible | adult stage, with Scer\GAL4^GMR.PF

(Tan et al., 2024)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PF

(Tan et al., 2024)

lobe system of adult mushroom body, with Scer\GAL4^elav-C155

(Tan et al., 2024)

lobe system of adult mushroom body, with Scer\GAL4^ey-OK107

(Tan et al., 2024)

medial lobe of adult mushroom body, with Scer\GAL4^elav-C155

(Tan et al., 2024)

medial lobe of adult mushroom body, with Scer\GAL4^ey-OK107

(Tan et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

HDAC4^UAS.Tag:MYC, Scer\GAL4^ey-OK107 has abnormal neuroanatomy | adult stage phenotype, enhanceable by Mef2^{UAS.cMa.Tag:HA}, Scer\GAL4^ey-OK107

(Tan et al., 2024)

NOT Enhanced by

Statement

Reference

HDAC4^UAS.Tag:MYC, Scer\GAL4^elav-C155 has abnormal neuroanatomy | adult stage phenotype, non-enhanceable by CG5846^UAS.Tag:HA, Scer\GAL4^elav-C155

(Tan et al., 2024)

NOT suppressed by

Statement

Reference

HDAC4^UAS.Tag:MYC, Scer\GAL4^elav-C155 has abnormal neuroanatomy | adult stage phenotype, non-suppressible by CG5846^UAS.Tag:HA, Scer\GAL4^elav-C155

(Tan et al., 2024)

Phenotype Manifest In

Enhanced by

Statement

Reference

HDAC4^UAS.Tag:MYC, Scer\GAL4^ey-OK107 has medial lobe of adult mushroom body phenotype, enhanceable by Mef2^{UAS.cMa.Tag:HA}, Scer\GAL4^ey-OK107

(Tan et al., 2024)

NOT Enhanced by

Statement

Reference

HDAC4^UAS.Tag:MYC, Scer\GAL4^elav-C155 has lobe system of adult mushroom body phenotype, non-enhanceable by CG5846^UAS.Tag:HA, Scer\GAL4^elav-C155

(Tan et al., 2024)

NOT suppressed by

Statement

Reference

HDAC4^UAS.Tag:MYC, Scer\GAL4^elav-C155 has lobe system of adult mushroom body phenotype, non-suppressible by CG5846^UAS.Tag:HA, Scer\GAL4^elav-C155

(Tan et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

HDAC4^UAS.Tag:MYC

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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