FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\acsKO
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General Information
Symbol
Dmel\acsKO
Species
D. melanogaster
Name
FlyBase ID
FBal0392825
Feature type
allele
Associated gene
Dmel\acs
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Socha et al., 2023)
Mutagen
CRISPR/Cas9
(Socha et al., 2023)
Progenitor genotype
Cytology
Description

A 5bp deletion in acs causing a frame-shift mutation, resulting in a presumably truncated non-functional protein.

(Socha et al., 2023)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3L:1,972,284..1,972,291 [+]
Comment:

CTTCCTGA is replaced with 'TTC' starting at codon H51 of acs, leading to a frameshift mutation.

Inserted_sequence:

TTC

(Socha et al., 2023)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CG1139 KO
      (Socha et al., 2023)
      acs iso CRISPR KO
      (Socha et al., 2023)
      acsKO
      Name Synonyms
      Secondary FlyBase IDs
        References (1)