FlyBase Allele Report: Dmel\Mecr[LL04663]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Mecr^LL04663

General Information

Symbol

Dmel\Mecr^LL04663

Species

D. melanogaster

Name

FlyBase ID

FBal0394462

Feature type

allele

Associated gene

Associated Insertion(s)

PBac{SAstopDsRed}Mecr^LL04663

Carried in Construct

Key Links

Genomic Maps

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

PBac{SAstopDsRed}Mecr^LL04663

Cytology

Description

Allele components

Component

Use(s)

Inserted element

PBac{SAstopDsRed}

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:13,861,519..13,861,519 [+]

(Dutta et al., 2023)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of childhood-onset dystonia with optic atrophy and basal ganglia abnormalities

CEC

(Dutta et al., 2023)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neurophysiology | adult stage | somatic clone - tissue specific

(Dutta et al., 2023)

decreased cell number | adult stage | somatic clone - tissue specific

(Dutta et al., 2023)

lethal - all die before end of larval stage

(Dutta et al., 2023)

lethal - all die before end of larval stage (with Df(2R)BSC307)

(Dutta et al., 2023)

lethal - all die before end of larval stage (with Mecr^{CR70041-TG4.1})

(Dutta et al., 2023)

some die during second instar larval stage

(Dutta et al., 2023)

some die during second instar larval stage (with Df(2R)BSC307)

(Dutta et al., 2023)

some die during second instar larval stage (with Mecr^{CR70041-TG4.1})

(Dutta et al., 2023)

some die during third instar larval stage

(Dutta et al., 2023)

some die during third instar larval stage (with Df(2R)BSC307)

(Dutta et al., 2023)

some die during third instar larval stage (with Mecr^{CR70041-TG4.1})

(Dutta et al., 2023)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

141310

y^* w^*; P{neoFRT}40A P{FRT(w^hs)}G13 cn¹ PBac{SAstopDsRed}Mecr^LL04663 bw¹/CyO, S^* bw¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Mecr^LL04663

mecr^A

(Dutta et al., 2023)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections