FlyBase Allele Report: Dmel\beat-IIa[+2]

General Information

Symbol

Dmel\beat-IIa⁺²

Species

D. melanogaster

Name

FlyBase ID

FBal0400424

Feature type

allele

Associated gene

Dmel\beat-IIa

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

Mutagen

CRISPR/Cas9

(Osaka et al., 2024)

Progenitor genotype

Cytology

Description

2bp insertion within the first exon of beat-IIa.

(Osaka et al., 2024)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

insertion

3R:17,345,509..17,345,510 [-]

Comment:

2bp insertion within the first exon of beat-IIa-RB at codon R2, resulting in a frameshift.

(Osaka et al., 2024)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell migration | embryonic stage (with Df(3R)ED5780)

(Huang et al., 2026)

Phenotype Manifest In

longitudinal trunk visceral muscle primordium (with Df(3R)ED5780)

(Huang et al., 2026)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Df(3R)ED5780, beat-IIa⁺², beat-IIb^Δ5+3 has abnormal size | larval stage phenotype, suppressible by beat-IIa^UAS.mCherry/Scer\GAL4^d.HLH54F

(Huang et al., 2026)

Suppressor of

Statement

Reference

beat-IIa⁺²/beat-IIa⁺² is a suppressor of abnormal neuroanatomy phenotype of Scer\GAL4^FRT.GMR.PC, side-IV^UAS.cOa

(Osaka et al., 2024)

beat-IIa⁺²/beat-IIa⁺² is a suppressor of abnormal neuroanatomy phenotype of Scer\GAL4^GMR.long, side-IV^UAS.cOa

(Osaka et al., 2024)

Other

Statement

Reference

Df(3R)ED5780, beat-IIa⁺², beat-IIb^Δ5+3 has abnormal size | larval stage phenotype

(Huang et al., 2026)

Df(3R)ED5780, beat-IIa⁺², beat-IIb^Δ5+3 has abnormal cell migration | embryonic stage phenotype

(Huang et al., 2026)

beat-IIa⁺², beat-IIb^Δ5+3 has abnormal size | larval stage phenotype

(Huang et al., 2026)

beat-IIa⁺², beat-IIb^Δ5+3 has abnormal cell migration | embryonic stage phenotype

(Huang et al., 2026)

Scer\GAL4^FRT.Act5C, beat-IIa⁺², beat-IIb^KK112363 has abnormal neuroanatomy phenotype

(Osaka et al., 2024)

Phenotype Manifest In

Suppressed by

Statement

Reference

Df(3R)ED5780, beat-IIa⁺², beat-IIb^Δ5+3 has longitudinal intestinal visceral muscle fiber | larval stage | decreased number phenotype, suppressible | partially by beat-IIa^UAS.mCherry/Scer\GAL4^d.HLH54F

(Huang et al., 2026)

Suppressor of

Statement

Reference

beat-IIa⁺²/beat-IIa⁺² is a suppressor of photoreceptor cell R7 phenotype of Scer\GAL4^FRT.GMR.PC, side-IV^UAS.cOa

(Osaka et al., 2024)

beat-IIa⁺²/beat-IIa⁺² is a suppressor of medulla phenotype of Scer\GAL4^FRT.GMR.PC, side-IV^UAS.cOa

(Osaka et al., 2024)

beat-IIa⁺²/beat-IIa⁺² is a suppressor of synapse | ectopic phenotype of Scer\GAL4^FRT.GMR.PC, side-IV^UAS.cOa

(Osaka et al., 2024)

beat-IIa⁺²/beat-IIa⁺² is a suppressor of photoreceptor cell R7 phenotype of Scer\GAL4^GMR.long, side-IV^UAS.cOa

(Osaka et al., 2024)

beat-IIa⁺²/beat-IIa⁺² is a suppressor of medulla phenotype of Scer\GAL4^GMR.long, side-IV^UAS.cOa

(Osaka et al., 2024)

beat-IIa⁺²/beat-IIa⁺² is a suppressor of axon phenotype of Scer\GAL4^GMR.long, side-IV^UAS.cOa

(Osaka et al., 2024)

Other

Statement

Reference

beat-IIa⁺², beat-IIb^Δ5+3 has longitudinal intestinal visceral muscle fiber | larval stage | decreased number phenotype

(Huang et al., 2026)

Df(3R)ED5780, beat-IIa⁺², beat-IIb^Δ5+3 has longitudinal trunk visceral muscle primordium phenotype

(Huang et al., 2026)

Df(3R)ED5780, beat-IIa⁺², beat-IIb^Δ5+3 has longitudinal intestinal visceral muscle fiber | larval stage | decreased number phenotype

(Huang et al., 2026)

beat-IIa⁺², beat-IIb^Δ5+3 has longitudinal trunk visceral muscle primordium phenotype

(Huang et al., 2026)

Scer\GAL4^FRT.Act5C, beat-IIa⁺², beat-IIb^KK112363 has synapse phenotype

(Osaka et al., 2024)

Scer\GAL4^FRT.Act5C, beat-IIa⁺², beat-IIb^KK112363 has lamina monopolar neuron phenotype

(Osaka et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

beat IIa⁺²

(Huang et al., 2026)

beat-IIa⁺²

(Osaka et al., 2024)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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