FB2026_03 , released September 17, 2026
Allele: Dmel\Su(var)205chromo.GFP
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General Information
Symbol
Dmel\Su(var)205chromo.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0404426
Feature type
allele
Associated gene
Dmel\Su(var)205
Associated Insertion(s)
TI{TI}Su(var)205chromo.GFP
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Stutzman et al., 2024)
gene targeting by homologous recombination
(Stutzman et al., 2024)
Progenitor genotype
Associated Insertion(s)
TI{TI}Su(var)205chromo.GFP
Cytology
Description

A GFP tag (followed by a flexible GGSGGSG linker) has been inserted into the endogenous Su(var)205 locus, at the N-terminal end of the coding sequence. In addition, a V26M amino acid substitution has been introduced into the Su(var)205 coding sequence.

(Stutzman et al., 2024)
Allele components
Component
Use(s)
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:8,210,768..8,210,768 [-]
Nucleotide change:

G8210768A

Amino acid change:

V26M | Su(var)205-PA; V26M | Su(var)205-PB

Reported amino acid change:

V26M

Comment:

Site of the V26M mutation within Su(var)205[chromo.GFP]. This allele also has a GFP tag (followed by a flexible GGSGGSG linker) inserted into the endogenous Su(var)205 locus, at the N-terminal end of the coding sequence. Site and nature of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.

(Stutzman et al., 2024)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
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      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Su(var)205chromo.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)