FB2026_03 , released September 17, 2026
Allele: Dmel\RdlI276C.Q
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General Information
Symbol
Dmel\RdlI276C.Q
Species
D. melanogaster
Name
FlyBase ID
FBal0404544
Feature type
allele
Associated gene
Dmel\Rdl
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Zhou et al., 2024)
gene targeting by homologous recombination
(Zhou et al., 2024)
Progenitor genotype
TI{TI}Rdl3xP3RFP
(Zhou et al., 2024)
Cytology
Description

Amino acid replacement: I276C.

(Zhou et al., 2024)

CRISPR/Cas9-mediated homology-directed repair has resulted in a chromosome with a Rdl locus that carries the I276C point mutation.

(Zhou et al., 2024)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
MNV
3L:9,155,237..9,155,239 [-]
Nucleotide change:

ATA9155239TGT

Reported nucleotide change:

ATA?TGT

Amino acid change:

I276C | Rdl-PA; I276C | Rdl-PC; I276C | Rdl-PD; I276C | Rdl-PE; I276C | Rdl-PF; I276C | Rdl-PG

Reported amino acid change:

I276C

Comment:

CRISPR/Cas9-mediated homology-directed repair has resulted in a chromosome with a Rdl locus that carries the I276C codon substitution (ATA to TGT).

(Zhou et al., 2024)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
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      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      RdlI276C.Q
      RdlI276C
      (Zhou et al., 2024)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)