UAS regulatory sequences plus the Drosophila Synthetic Core Promoter (DSCP) (from the pNP vector) regulate expression of two shRNAs; the first targets kto (this hairpin contains an inverted repeat of CAGATGCTACGACAACGACAA) and the second targets CycC (this hairpin contains an inverted repeat of CACGGCGACGGTTTACTTCAA).