FlyBase Allele Report: Dmel\Argk3[TH03323.N]

General Information

Symbol

Dmel\Argk3^TH03323.N

Species

D. melanogaster

Name

FlyBase ID

FBal0407585

Feature type

allele

Associated gene

Dmel\Argk3

Associated Insertion(s)

Carried in Construct

P{TH03323.N}

Key Links

Transgenic product class

RNAi_reagent

(Chen et al., 2025)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Chen et al., 2025)

Mutagen

in vitro construct

(Chen et al., 2025)

Progenitor genotype

Carried in construct

P{TH03323.N}

Cytology

Description

UAS drives expression of a shRNA that targets Argk3.

(Chen et al., 2025)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Argk3

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | spermatogenesis, with Scer\GAL4^bam.PU

(Chen et al., 2025)

increased cell death | spermatogenesis, with Scer\GAL4^bam.PU

(Chen et al., 2025)

lethal | paternal effect, with Scer\GAL4^bam.PU

(Chen et al., 2025)

lethal | paternal effect, with Scer\GAL4^nanos.PU

(Chen et al., 2025)

male sterile, with Scer\GAL4^bam.PU

(Chen et al., 2025)

male sterile, with Scer\GAL4^nanos.PU

(Chen et al., 2025)

Phenotype Manifest In

axonemal microtubule | spermatogenesis, with Scer\GAL4^bam.PU

(Chen et al., 2025)

cystic bulge, with Scer\GAL4^bam.PU

(Chen et al., 2025)

investment cone, with Scer\GAL4^bam.PU

(Chen et al., 2025)

male germ cell nucleus, with Scer\GAL4^bam.PU

(Chen et al., 2025)

seminal vesicle, with Scer\GAL4^bam.PU

(Chen et al., 2025)

spermatid, with Scer\GAL4^bam.PU

(Chen et al., 2025)

spermatid axoneme, with Scer\GAL4^bam.PU

(Chen et al., 2025)

spermatocyte, with Scer\GAL4^bam.PU

(Chen et al., 2025)

spermatozoon | absent, with Scer\GAL4^bam.PU

(Chen et al., 2025)

testis, with Scer\GAL4^bam.PU

(Chen et al., 2025)

waste bag | absent, with Scer\GAL4^bam.PU

(Chen et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Argk3^TH03323.N, Scer\GAL4^bam.PU has male sterile phenotype, suppressible by ocn^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^bam.PU

(Chen et al., 2025)

Argk3^TH03323.N, Scer\GAL4^bam.PU has lethal | paternal effect phenotype, suppressible by ocn^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^bam.PU

(Chen et al., 2025)

Argk3^TH03323.N, Scer\GAL4^bam.PU has male sterile phenotype, suppressible by Hsap\CKMT1B^UAS.cCa, Scer\GAL4^bam.PU

(Chen et al., 2025)

Argk3^TH03323.N, Scer\GAL4^bam.PU has lethal | paternal effect phenotype, suppressible by Hsap\CKMT1B^UAS.cCa, Scer\GAL4^bam.PU

(Chen et al., 2025)

Phenotype Manifest In

Suppressed by

Statement

Reference

Argk3^TH03323.N, Scer\GAL4^bam.PU has spermatozoon | absent phenotype, suppressible by ocn^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^bam.PU

(Chen et al., 2025)

Argk3^TH03323.N, Scer\GAL4^bam.PU has spermatid phenotype, suppressible by ocn^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^bam.PU

(Chen et al., 2025)

Argk3^TH03323.N, Scer\GAL4^bam.PU has male germ cell nucleus phenotype, suppressible by Hsap\CKMT1B^UAS.cCa, Scer\GAL4^bam.PU

(Chen et al., 2025)

Argk3^TH03323.N, Scer\GAL4^bam.PU has male germ cell nucleus phenotype, suppressible by ocn^{UAS.ORF.GW.Tag:HA}, Scer\GAL4^bam.PU

(Chen et al., 2025)

Argk3^TH03323.N, Scer\GAL4^bam.PU has investment cone phenotype, suppressible by Hsap\CKMT1B^UAS.cCa, Scer\GAL4^bam.PU

(Chen et al., 2025)

Argk3^TH03323.N, Scer\GAL4^bam.PU has spermatozoon | absent phenotype, suppressible by Hsap\CKMT1B^UAS.cCa, Scer\GAL4^bam.PU

(Chen et al., 2025)

Argk3^TH03323.N, Scer\GAL4^bam.PU has spermatid phenotype, suppressible by Hsap\CKMT1B^UAS.cCa, Scer\GAL4^bam.PU

(Chen et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Argk3^TH03323.N

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close