FlyBase Allele Report: Dmel\hh[RNAi.UAS.cUa]

General Information

Symbol

Dmel\hh^RNAi.UAS.cUa

Species

D. melanogaster

Name

FlyBase ID

FBal0407696

Feature type

allele

Associated gene

Dmel\hh

Associated Insertion(s)

Carried in Construct

P{UAS-hh.RNAi.U}

Key Links

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-hh.RNAi.U}

Cytology

Description

UAS regulatory sequences drive expression of an RNAi construct targeting hh.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of primary bacterial infectious disease

CEA

(Lee et al., 2015)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal immune response, with Scer\GAL4^NP0001

(Lee et al., 2015)

neoplasia | adult stage | female, with Scer\GAL4^C587, Scer\GAL4^bab1-Pgal4-2

(Li et al., 2015)

short lived, with Scer\GAL4^NP0001

(Lee et al., 2015)

Phenotype Manifest In

germarium, with Scer\GAL4^C587, Scer\GAL4^bab1-Pgal4-2

(Li et al., 2015)

Detailed Description

Statement

Reference

Host survival is compromised after E. carotovora infection in flies expressing hh^{dsRNA.Scer\UAS.cUa} under the control of the enterocyte-specific driver Scer\GAL4^{Myo31DF-NP0001}.

(Lee et al., 2015)

Expression of hh^TRiP.cUa under the control of either Scer\GAL4^C587 or Scer\GAL4^bab1-Pgal4-2 individually has no apparent germarium phenotype but is tumorigenic when both drivers are used simultaneously.

(Li et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^NP0001, hh^RNAi.UAS.cUa has abnormal immune response phenotype, suppressible by Cad99C^UAS.cUa, Scer\GAL4^NP0001

(Lee et al., 2015)

Scer\GAL4^NP0001, hh^RNAi.UAS.cUa has short lived phenotype, suppressible by Cad99C^UAS.cUa, Scer\GAL4^NP0001

(Lee et al., 2015)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

hh^RNAi.UAS.cUa

hh^TRiP.cUa

hh^{dsRNA.Scer\UAS.cUa}

hh^{dsRNA.UAS.cUa}

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Unknown

Secondary FlyBase IDs

FBal0302858
FBal0324763

References (5)

Report Sections

Open Close