FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Ecol\lacZPde4.PD
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General Information
Symbol
Ecol\lacZPde4.PD
Species
E. coli
Name
FlyBase ID
FBal0408161
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{Pde4-lacZ.D}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Kurusu et al., 2002)
Progenitor genotype
Carried in construct
P{Pde4-lacZ.D}
Cytology
Description

The dnc promoter drives expression of a lacZ reporter.

(Kurusu et al., 2002)
Allele components
Component
Use(s)
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage
      mushroom body calyx
      (Tettamanti et al., 1997)
      lobe system of mushroom body
      (Tettamanti et al., 1997)
      Kenyon cell
      (Tettamanti et al., 1997)
      calyx of larval mushroom body | restricted
      (Masuda-Nakagawa et al., 2005)
      immunolocalization
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage
      Kenyon cell | subset
      (Kurusu et al., 2002)
      mushroom body pedunculus | restricted
      (Kurusu et al., 2002)
      lobe system of mushroom body | restricted
      (Kurusu et al., 2002)
      Additional Information
      Statement
      Reference

      Throughout the larval stages expression with the Kenyon cells is within a small cluster peripherally positioned in each of the clusters deriving from the embryonic mushroom body neuroblasts. Expression is detected in the outermost surface layer of the pedunculus and the mushroom body lobes.

      (Kurusu et al., 2002)

      Larval expression is observed in Kenyon cells, calyces, and lobe-like structures of the mushroom body.

      (Tettamanti et al., 1997)
       
      Marker for
      Kenyon cell
      (Tettamanti et al., 1997)
      Reflects expression of
      Pde4
      (Tettamanti et al., 1997)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (7)
      Reported As
      Symbol Synonym
      Ecol\lacZPde4.PD
      Ecol\lacZPde4.tr60
      Ecol\lacZdnc.PD
      Ecol\lacZdnc.tr60
      lacZdnc.tr60
      tr60#3
      Name Synonyms
      dunce promoter construct of Davis
      (Kurusu et al., 2002)
      Secondary FlyBase IDs
      • FBal0136000
      • FBal0065769
      References (5)