FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mpv17L
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General Information
Symbol
Dmel\Mpv17L
Species
D. melanogaster
Name
FlyBase ID
FBal0409174
Feature type
allele
Associated gene
Dmel\Mpv17
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Fourth Chromosome Resource Project and Newfeld, 2022-)
Progenitor genotype
Caused by aberration
Df(4)Mpv17L
Cytology
Description

Frameshift deletion (8bp) of 4:1029022..1029029 and SNP 4:1029021 C to G resulting in the addition of RGRYQNAGRPDPFCATLYHGHVFFGATLQRRAHRPNPAAHS after serine 73 of the only Mpv17 isoform and premature truncation following these novel amino acids. This deletion also affects asRNA:CR44031 on the opposite strand: it results in the loss of bases 333 through 340 of the asRNA:CR44031 RA transcript and bases 361 through 368 of the RB transcript.

(Fourth Chromosome Resource Project and Newfeld, 2022-)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Mpv17L
      Name Synonyms
      Secondary FlyBase IDs
        References (1)