FB2026_02 , released June 18, 2026
Allele: Ggal\Camftz.Tag:MT(Khc)
Open Close
General Information
Symbol
Ggal\Camftz.Tag:MT(Khc)
Species
G. gallus
Name
FlyBase ID
FBal0410720
Feature type
allele
Associated gene
Ggal\Cam
Associated Insertion(s)
Carried in Construct
P{Khc.KC}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(VanBerkum and Goodman, 1995)
Progenitor genotype
Carried in construct
P{Khc.KC}
Cytology
Description

The ftz neurogenic control element drives expression of wild-type Ggal\Cam that is tagged at the N-terminal end with Tag:MT(Khc) to target the expressed protein to the growth cone when it is expressed in neurons. The expressed protein is expected to act as an inhibitor of Cam (and other Ca[2+]-binding proteins) by competing for available Ca[2+].

(VanBerkum and Goodman, 1995)
Allele components
Component
Use(s)
Regulatory region(s)
ftz
Encoded product / tool
Ggal\Cam
Tagged with
Tag:MT(Khc)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Defects in the formation of the longitudinal axon pathways. At stage 13-14 dMP2 and vMP2 axon extension stalls and axon guidance shows errors. At stage 16 MP1 pathway freely crosses the midline.

      (VanBerkum and Goodman, 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ggal\Camftz.Tag:MT(Khc)
      Khc::Ggal\CamKC.ftz
      Name Synonyms
      kinesin-CaM
      (VanBerkum and Goodman, 1995)
      Secondary FlyBase IDs
      • FBal0410675
      • FBal0048831
      References (1)