FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

centrifugal neuron C2

ID (Ontology)

FBbt:00003743 (Fly Anatomy)

Definition

Adult centrifugal neuron with arborizations in the medulla layers M1, M5/M6, M8 and M10 and more restricted arborizations in the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). In the medulla, it makes reciprocal connections to lamina monopolar neuron L1, and is presynaptic to L2 and L5, as well as medullary intrinsic neuron Mi1 (Takemura et al., 2013). It is GABAergic (Fei et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).[ FlyBase:FBrf0049410 FlyBase:FBrf0054529 FlyBase:FBrf0205531 FlyBase:FBrf0210635 FlyBase:FBrf0216925 FlyBase:FBrf0222324 FlyBase:FBrf0252485 FlyBase:FBrf0262545 ]

Also Known As

"C2"

Comment

Pre- versus postsynaptic innervation in the proximal medulla was inferred by scoring of terminal morphology from figures in Fischbach and Dittrich (1989) as assessed by FlyBrain Neuron DB. Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013).

Links to External Ontologies

VFB:FBbt_00003743

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Alleles (FBal)	PHENOTYPE_MANIFEST_IN
Insertions (FBti)	EXPRESSION_STAGE_TISSUE_POSITION
Constructs (FBtp)	PHENOTYPE_MANIFEST_IN

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Alleles	Split System Combinations	Genes		Insertions	Constructs
centrifugal neuron C2 (all annotations which use CV term, excluding "NOT" statements)

Spanning Tree (Parents/Children)

GABAergic neuron
 |__adult GABAergic neuron__________________
optic lobe intrinsic columnar neuron        |
 |__optic lobe centrifugal columnar neuron__|
adult neuron                                |
 |__adult GABAergic neuron__________________|
                                            centrifugal neuron C2  40 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	optic lobe centrifugal columnar neuron adult GABAergic neuron
Part of
Synonyms & Secondary IDs
Synonyms
	"C2" EXACT VFB_SYMBOL[ FlyBase:FBrf0247762 ]
Secondary IDs

External Crossreferences & Linkouts
	FlyBrain_NDB:10079 VFB:FBbt_00003743