FB2026_03 , released September 17, 2026
CV Term Report
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Term centrifugal neuron C3 ID (Ontology) FBbt:00003744 (Fly Anatomy)
Definition Adult centrifugal neuron with arborizations in medulla layers M1-2, M5, and M9-10 and more restricted arborizations in the lamina (Fischbach and Dittrich, 1989; Kind et al., 2021). It forms presynapses and postsynapses in the lamina (Morante and Desplan, 2008; Rivera-Alba et al., 2011). In the medulla it is strongly presynaptic to monopolar lamina neuron L2 and columnar neuron T1, and strongly postsynaptic to L1 (Takemura et al., 2013). It is GABAergic (Fei et al., 2010). There is usually one of these cells per optic column (Nern et al., 2025).[ FlyBase:FBrf0049410 FlyBase:FBrf0054529 FlyBase:FBrf0204652 FlyBase:FBrf0205531 FlyBase:FBrf0210635 FlyBase:FBrf0216925 FlyBase:FBrf0222324 FlyBase:FBrf0252485 FlyBase:FBrf0262545 ]
Also Known As"C3"
CommentPre-synaptic terminals were assessed by labelling with a UAS-Synaptotagmin reporter (P\{UAS-HA-syt\} - FBtp0015803). The identification of dendrites was done using a UAS-Dscam (P\{UAS-Dscam.exon17.1.GFP\} - FBtp0021447) reporter (Morante and Desplan, 2008). Cell connectivity in the lamina was determined by analysis of semi-automated EM reconstruction of 749 serial sections of 21 complete lamina cartridges. Connectivity in the medulla was extrapolated from serial EM of 7 columns from a single sample (Takemura et al., 2013).
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VFB:FBbt_00003744
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 centrifugal neuron C3 (all annotations which use CV term, excluding "NOT" statements)
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adult optic lobe columnar neuron
 |__optic lobe wide-field columnar neuron___
GABAergic neuron                            |
 |__adult GABAergic neuron__________________|
optic lobe intrinsic columnar neuron        |
 |__optic lobe centrifugal columnar neuron__|
adult neuron                                |
 |__adult GABAergic neuron__________________|
                                            centrifugal neuron C3  42 rec.
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Is a optic lobe centrifugal columnar neuron
adult GABAergic neuron
optic lobe wide-field columnar neuron
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FlyBrain_NDB:10080
VFB:FBbt_00003744