FB2026_02 , released June 18, 2026
Chemical: Epinephrine
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General Information
Name
Epinephrine
FlyBase ID
FBch0000283
ChEBI Name
(R)-adrenaline
ChEBI ID
PubChem Name
Epinephrine
PubChem ID
Chemical Structure
Chemical structure of Epinephrine
Epinephrine
InChIKey

UCTWMZQNUQWSLP-VIFPVBQESA-N

Definition (ChEBI)

ChEBI: (R)-adrenaline is the R-enantiomer of adrenaline. It is a hormone secreted by the adrenal glands resulting in the 'fight-or-flight' response. It has a role as a hormone, an adrenergic agonist, a vasodilator agent, an alpha-adrenergic agonist, a bronchodilator agent, a vasoconstrictor agent, a beta-adrenergic agonist, a sympathomimetic agent, a mydriatic agent and a mouse metabolite. It is a conjugate base of a (R)-adrenaline(1+). It is an enantiomer of a (S)-adrenaline.NCI Thesaurus (NCIt): Therapeutic Epinephrine is the synthetic form of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing, and bronchodilating activities. By stimulating vascular alpha-adrenergic receptors, epinephrine causes vasoconstriction, thereby increasing vascular resistance and blood pressure. When administered in the conjunctiva, this agent binds to alpha-adrenergic receptors in the iris sphincter muscle, resulting in vasoconstriction, a decrease in the production of aqueous humor, and a lowering of intraocular pressure. Through its beta1 receptor-stimulating actions, epinephrine increases the force and rate of myocardial contraction and relaxes bronchial smooth muscle, resulting in bronchodilation. The R-enantiomer of adrenaline. It is a hormone secreted by the adrenal glands resulting in the 'fight-or-flight' response.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (35)
Synonyms
(-)-(R)-epinephrine
(-)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-adrenaline
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(-)-adrenaline
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
Adnephrine
Chelafrin
Epinefrina
Epinephrin
Epipen
Epipen JR
L-Adrenaline
L-epinephrine
Levoepinephrine
Primatene
adnephrine
adrenalin
chelafrin
epinephrinum
epiniephrine
l-Adrenaline
l-adrenaline
l-epinephrine
levoepinephrine
Secondary FlyBase IDs
    References (5)