FB2026_02 , released June 18, 2026
Chemical: wortmannin
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General Information
Name
wortmannin
FlyBase ID
FBch0001342
ChEBI Name
wortmannin
ChEBI ID
CHEBI:52289
PubChem Name
Wortmannin
PubChem ID
CID:312145
Chemical Structure
Chemical structure of wortmannin
wortmannin
InChIKey

QDLHCMPXEPAAMD-QAIWCSMKSA-N

Definition (ChEBI)

ChEBI: Wortmannin is an organic heteropentacyclic compound, a delta-lactone, an acetate ester and a cyclic ketone. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor, an anticoronaviral agent, a geroprotector, an autophagy inhibitor, a Penicillium metabolite, a radiosensitizing agent and an antineoplastic agent.

Roles Classification (ChEBI)
Comment

Wortmannin

(Tamada et al., 2021)
Synonyms and Secondary IDs (22)
Synonyms
(1S,6bR,9aS,11R,11bR)-9a,11b-dimethyl-1-[(methyloxy)methyl]-3,6,9-trioxo-1,6,6b,7,8,9,9a,10,11,11b-decahydro-3H-furo[4,3,2-de]indeno[4,5-h]isochromen-11-yl acetate
(ChEBI, 2019-)
19545-26-7
(PubChem, 2019-)
Antibiotic SL-2052
(PubChem, 2019-)
KY 12420
(PubChem, 2019-)
MFCD00133927
(PubChem, 2019-)
NSC221019
(PubChem, 2019-)
PubChem:312145
(PubChem, 2019-)
SL-2052
(PubChem, 2019-)
UNII-XVA4O219QW
(PubChem, 2019-)
Wartmannin
(ChEBI, 2019-, PubChem, 2019-)
Wortmannin
(Bearden et al., 2024, Towler et al., 2020)
XVA4O219QW
(PubChem, 2019-)
antibiotic sl-2052
(PubChem, 2019-)
ky 12420
(PubChem, 2019-)
mfcd00133927
(PubChem, 2019-)
nsc221019
(PubChem, 2019-)
pubchem:312145
(PubChem, 2019-)
sl-2052
(PubChem, 2019-)
unii-xva4o219qw
(PubChem, 2019-)
wartmannin
(PubChem, 2019-)
wortmannin
(Chen et al., 2022, Qin et al., 2020, ChEBI, 2019-, Huang et al., 2019, PubChem, 2019-, Sharma et al., 2019, Sim et al., 2019, Iacobucci and Gunawardena, 2018, Bangi et al., 2016, Danilov et al., 2013, Hirabayashi et al., 2013, Moskalev and Shaposhnikov, 2010, Witte et al., 2009, Britton et al., 2002)
xva4o219qw
(PubChem, 2019-)
Secondary FlyBase IDs
    References (17)