FB2026_03 , released September 17, 2026
Chemical: donepezil hydrochloride
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General Information
Name
donepezil hydrochloride
FlyBase ID
FBch0002660
ChEBI Name
donepezil hydrochloride
ChEBI ID
CHEBI:4696
PubChem Name
Donepezil Hydrochloride
PubChem ID
CID:5741
Chemical Structure
Chemical structure of donepezil hydrochloride
donepezil hydrochloride
InChIKey

XWAIAVWHZJNZQQ-UHFFFAOYSA-N

Definition (ChEBI)

A racemate comprising equimolar amounts of (R)- and (S)- donepezil hydrochloride. Its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.

Roles Classification (ChEBI)
Comment
Synonyms and Secondary IDs (18)
Synonyms
(+-)-2-((1-Benzyl-4-piperidyl)methyl)-5,6-dimethoxy-1-indanone hydrochloride
(ChEBI, 2019-)
1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hcl
(ChEBI, 2019-)
110119-84-1
(PubChem, 2019-)
120011-70-3
(PubChem, 2019-)
2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride
(PubChem, 2019-)
Aricept
(PubChem, 2019-)
Aricept ODT
(PubChem, 2019-)
BNAG
(PubChem, 2019-)
Donepezil HCl
(ChEBI, 2019-, PubChem, 2019-)
Donepezil hydrochloride
(PubChem, 2019-)
E 2020
(PubChem, 2019-)
E-2020
(PubChem, 2019-)
PubChem:5741
(PubChem, 2019-)
arisept
(Radysh et al., 2006)
donepezil
(Ogunsuyi et al., 2026)
donepezil hydrochloride
(Phan et al., 2025, Siddique et al., 2024, ChEBI, 2019-, PubChem, 2019-, Radysh et al., 2006)
rac-1-benzyl-4-[(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl]piperidinium chloride
(ChEBI, 2019-)
rac-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one hydrochloride
(ChEBI, 2019-)
Secondary FlyBase IDs
    References (6)