FB2026_03 , released September 17, 2026
Split System Combination: Scer\GAL4DBD.R26B12∩Hsap\RELAAD.R26A02
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General Information
Symbol
Scer\GAL4DBD.R26B12∩Hsap\RELAAD.R26A02
FlyBase ID
FBco0001725
Feature Type
split system combination
Component Alleles
Combination components
Component allele Hsap\RELAAD.R26A02
Component
Use(s)
Regulatory region(s)
GMR26A02
Encoded product / tool
p65(AD)::Zip+
Description

The GMR26A02 enhancer fragment followed by the Drosophila synthetic core promoter (DSCP) is fused upstream of the p65(AD)::Zip+ hemidriver (component of a 'split driver' system, contains the p65 activation domain).

(Rubin Laboratory at Janelia Farm, 2017)
Component allele Scer\GAL4DBD.R26B12
Component
Use(s)
Regulatory region(s)
GMR26B12
Encoded product / tool
GAL4(DBD)::Zip-
Description

The GMR26B12 enhancer fragment followed by the Drosophila synthetic core promoter (DSCP) is fused upstream of the GAL4(DBD)::Zip- hemidriver (component of the 'Split GAL4' system, contains the GAL4 DNA-binding domain).

(Rubin Laboratory at Janelia Farm, 2017)
Expression Data
Reporters Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult brain | restricted
(Hampel et al., 2015)
adult optic lobe | restricted
(Hampel et al., 2015)
adult pars intercerebralis | restricted
(Hampel et al., 2015)
antennal grooming brain interneuron 2
(Hampel et al., 2015)
adult ventral nerve cord | restricted
(Hampel et al., 2015)
Additional Information
Statement
Reference

In a split-GAL4 system, HsapRELAAD.R26A02 drives expression in antennal grooming brain interneuron 2, the optic lobe, the adult pars intercerebralis, the thoracico-abdominal ganglion and the lateral part of the brain when combined with ScerGAL4DBD.R26B12.

(Hampel et al., 2015)

In a split-GAL4 system, ScerGAL4DBD.R26B12 drives expression in antennal grooming brain interneuron 2, the optic lobe, the adult pars intercerebralis, the thoracico-abdominal ganglion and the lateral part of the brain when combined with HsapRELAAD.R26A02, and in antennal grooming brain interneuron 2, the adult central complex and the posterior part of the brain when combined with HsapRELAAD.R24C08. Antennal grooming brain interneuron 2 were seen in close proximity to EcollexAGMR27H08 expressing zone C/E Johnston organ neurons. Positive GRASP (GFP reconstitution across synaptic partners) signals were seen between C/E Johnston organ neurons and antennal grooming brain interneuron 2 using these drivers.

(Hampel et al., 2015)
Marker for
Stocks (0)
External Crossreferences and Linkouts ( 0 )
References (1)