The R76F05 enhancer fragment is fused upstream of the Drosophila synthetic core promoter (DSCP) followed by the p65(AD)::Zip+ hemidriver (component of a 'split driver' system, contains the p65 activation domain). A Hsp70 transcriptional terminator is present.
A genomic fragment from within the ple gene regulates expression of the GAL4(DBD)::Zip- hemidriver.