The T-box transcription factors are sequence-specific DNA binding proteins that regulate transcription. They are characterized by a conserved DNA-binding immunoglobulin-fold domain of 180-200 amino acids, known as T-box, named after its founding member, the mouse T protein. (Adapted from FBrf0218841).
Notes on Group
The T-BOX TRANSCRIPTION FACTORS gene group includes Doc1, Doc2 and Doc3 encoded by the Dorsocross (Doc) gene cluster.