Golgins are long, parallel coiled-coil homodimers important in regulating vesicle mediated transport and Golgi architecture. They are anchored to specific sites on the Golgi complex surface either by a C-terminal transmembrane domain or interacting with Arf/Arf-like GTPases via a GRIP/GRAB domain. Golgins are thought to act as tethering factors, interacting with vesicles by binding Rab GTPases and guiding them to the correct Golgi cisternae. (Adapted from PMID:21436057).