FB2026_03 , released September 17, 2026
Gene Group: SERPINS
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General Information
Name
SERPINS
Species
D. melanogaster
Symbol
SPN
FlyBase ID
FBgg0000103
Date last reviewed
2013-02-15
Number of members
30
Description
Description
The serpin family is a structurally-related group of secreted proteins containing the serpin-fold, a 350-400 amino acid domain. Serpins (SERine Protease INhibitors) were first identified as a set of proteins able to inhibit proteases, acting by forming a covalent complex is formed with the target proteinase targeting it for degradation. (Adapted from FBrf0213937 and FBrf0209216).
Notes on Group
Source Material
The SERPINS Gene Group has been compiled using the following publication(s): Gubb, 2012.9.27, Reichhart et al., 2011, and Garrett et al., 2009 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Component group(s)
INHIBITORY SERPINS
NON-INHIBITORY SERPINS
Members (30)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
SPN
SERPINS
Serine protease inhibitors
Serine peptidase inhibitors
Cysteine peptidase inhibitors
Serp
Srp
Secondary FlyBase ID(s)
References (4)