FB2026_02 , released June 18, 2026
Gene Group: RHG PROTEINS
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General Information
Name
RHG PROTEINS
Species
D. melanogaster
Symbol
RHG
FlyBase ID
FBgg0000177
Date last reviewed
2014-07-27
Number of members
6
Description
Description
RHG proteins possess a 12 amino acid RHG motif. This motif, also known as the IAP-binding motif (IBM), interacts with the BIR domain of Inhibitor of apoptosis proteins (IAPs) and relieving IAP-mediated caspase inhibition. Over-expression of individual RHG proteins is sufficient to induce apoptosis. (Adapted from FBrf0225510).
Notes on Group
Source Material
The RHG PROTEINS Gene Group has been compiled using the following publication(s): Xu et al., 2009 and Zhou, 2005 .
Key Gene Ontology (GO) terms
Molecular Function
BIR domain binding
Biological Process
positive regulation of apoptotic process
Cellular Component
Related Gene Groups
Other related group(s)
INHIBITOR OF APOPTOSIS
Members (6)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
IAP-binding motif proteins
RGH motif-containing proteins
IBM
RGH PROTEINS
RGH
RHG PROTEINS
RHG
Secondary FlyBase ID(s)
References (3)