Inhibitor of APoptosis (IAP) proteins are defined by the presence of one or more BIR (baculoviral IAP repeat) domains. Not all IAPs inhibit apoptosis, but some interact with and inhibit caspases via their BIR domains. This interaction is displaced by RHG protein binding. (Adapted from FBrf0215539).
Notes on Group
INHIBITOR OF APOPTOSIS
Gene Group has been compiled by FlyBase curators using
the following publication(s):
Xu et al., 2009