Gene Group: METABOTROPIC GLUTAMATE RECEPTORS

General Information

Name

METABOTROPIC GLUTAMATE RECEPTORS

Species

D. melanogaster

Symbol

MGLUR

FlyBase ID

FBgg0000186

Date last reviewed

2024-09-12

Number of members

Description

Metabotropic glutamate receptors (mGluRs) are Class C GPCRs. They bind the neurotransmitter glutamate as an obligate homodimer. (Adapted from PMID:20055706 and FBrf0162280).

Notes on Group

mtt has been included as a member of the METABOTROPIC GLUTAMATE RECEPTORS gene group as phylogenetically it belongs to this group. However, it lacks key glutamate binding residues and does not bind glutamate (FBrf0174795 and FBrf0221506).

The MXR METABOTROPIC GLUTAMATE-LIKE RECEPTORS gene group contains only one member.

Source Material

The METABOTROPIC GLUTAMATE RECEPTORS Gene Group has been compiled using the following publication(s): Hanlon and Andrew, 2015, Mitri et al., 2004, and Brody and Cravchik, 2000 .

Key Gene Ontology (GO) terms

Molecular Function

glutamate receptor activity

Biological Process

G protein-coupled glutamate receptor signaling pathway

Cellular Component

G protein-coupled receptor homodimeric complex

plasma membrane

Related Gene Groups

Parent group(s)

CLASS C GPCRs

Members (1)