FB2026_03 , released September 17, 2026
Gene Group: CLASS C GPCRs
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General Information
Name
CLASS C GPCRs
Species
D. melanogaster
Symbol
GPCR-C
FlyBase ID
FBgg0000180
Date last reviewed
2013-08-15
Number of members
11
Description
Description
In general, Class C GPCRs possess a large ligand-binding extracellular domain and form constitutive dimers. (Adapted from PMID:22286915).
Notes on Group
Source Material
The CLASS C GPCRs Gene Group has been compiled using the following publication(s): Schlichting et al., 2022, Hanlon and Andrew, 2015, Agrawal et al., 2013, Mitri et al., 2004, Mezler et al., 2001, Brody and Cravchik, 2000, and Josefsson, 1999 .
Key Gene Ontology (GO) terms
Molecular Function
G protein-coupled receptor activity
Biological Process
G protein-coupled receptor signaling pathway
Cellular Component
plasma membrane
Related Gene Groups
Parent group(s)
G PROTEIN COUPLED RECEPTORS
Component group(s)
BOSS-TYPE RECEPTORS
GABA(B) RECEPTORS
METABOTROPIC GLUTAMATE RECEPTORS
MXR METABOTROPIC GLUTAMATE-LIKE RECEPTORS
UNCLASSIFIED CLASS C GPCRs
Members (11)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
GPCR-C
CLASS C GPCRs
Family C GPCR
Family 3 GPCR
Secondary FlyBase ID(s)
References (8)