Gene Group: ANTENNAPEDIA COMPLEX

General Information

Name

ANTENNAPEDIA COMPLEX

Species

D. melanogaster

Symbol

ANT-C

FlyBase ID

FBgg0000365

Date last reviewed

2017-07-25

Number of members

Description

The Antennapedia complex (ANT-C) is one of two Hox gene complexes. Hox genes encode homeodomain transcription factors. ANT-C controls the identity of segments that contribute to the head and the anterior thorax. ANT-C homeotic genes show colinearity in their expression patterns with the exception of pb. (Adapted from FBrf0190304).

Notes on Group

The organization of the ANT-C is somewhat more complex than other non-Drosophila HOX gene complexes and the Hox genes are found in both transcriptional orientations. ANT-C also contains additional Hox-like homeobox genes: ftz, bcd, zen and zen2 (FBrf0202179, FBrf0075367, FBrf0194435), which are not included in the ANTENNAPEDIA COMPLEX gene group but can be found in HOX-LIKE HOMEOBOX TRANSCRIPTION FACTORS gene group.

Source Material

The ANTENNAPEDIA COMPLEX Gene Group has been compiled using the following publication(s): Negre and Ruiz, 2007, Pearson et al., 2005, Carroll, 1995, and Gehring et al., 1994 .

Key Gene Ontology (GO) terms

Molecular Function

DNA-binding transcription factor activity, RNA polymerase II-specific

RNA polymerase II transcription regulatory region sequence-specific DNA binding

Biological Process

regulation of transcription by RNA polymerase II

segment specification

Cellular Component

nucleus

Related Gene Groups

Parent group(s)

HOX GENE COMPLEX