Gene Group: DYNEIN HEAVY CHAINS

General Information

Name

DYNEIN HEAVY CHAINS

Species

D. melanogaster

Symbol

DYN-HC

FlyBase ID

FBgg0000377

Date last reviewed

2016-01-21

Number of members

Description

Dynein heavy chains are minus end-directed microtubule motor protein complexes. The dynein heavy chain family possesses a AAA+ ATPase superfamily motor domain attached to a divergent N-terminal tail domain. The tail domain mediates oligomerization and serves as a platform for the assembly of dynein complex subunits. (Adapted from PMID:24064538).

Notes on Group

Source Material

The DYNEIN HEAVY CHAINS Gene Group has been compiled using the following publication(s): Karak et al., 2015, Dyer et al., 2011, Wickstead and Gull, 2007, Pfister et al., 2006, de Carvalho et al., 2000, Goldstein and Gunawardena, 2000, Kurek et al., 1998, and Rasmusson et al., 1994 .

Key Gene Ontology (GO) terms

Molecular Function

minus-end-directed microtubule motor activity

Biological Process

microtubule-based movement

Cellular Component

dynein complex

Related Gene Groups

Parent group(s)

DYNEIN SUBUNITS

MICROTUBULE MOTORS

Component group(s)