FB2026_03 , released September 17, 2026
Gene Group: HEAT SHOCK PROTEIN 60 CHAPERONINS
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General Information
Name
HEAT SHOCK PROTEIN 60 CHAPERONINS
Species
D. melanogaster
Symbol
HSP60
FlyBase ID
FBgg0000503
Date last reviewed
2016-05-04
Number of members
12
Description
Description
The Heat Shock Protein 60 (Hsp60) family of chaperonins assist in the correct folding of newly synthesized or stress denatured proteins in an ATP-dependent manner. They are divided into two groups (I and II) that are structurally similar and quite diverse in sequence. Chaperonins form a large cage-like structure composed of two rings. (Adapted from FBrf0232269).
Notes on Group
Source Material
The HEAT SHOCK PROTEIN 60 CHAPERONINS Gene Group has been compiled using the following publication(s): Morrow et al., 2016, Monzo et al., 2010, Arya et al., 2007, and Sarkar and Lakhotia, 2005 .
Key Gene Ontology (GO) terms
Molecular Function
ATP-dependent protein folding chaperone
Biological Process
protein folding
Cellular Component
Related Gene Groups
Parent group(s)
ATP-DEPENDENT PROTEIN FOLDING CHAPERONES
HEAT SHOCK PROTEINS
Component group(s)
HEAT SHOCK PROTEIN 60 CHAPERONINS - GROUP I
HEAT SHOCK PROTEIN 60 CHAPERONINS - GROUP II
Members (12)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
HSP60
HEAT SHOCK PROTEIN 60 CHAPERONINS
Chaperonins
HSP60 Chaperones
60 kDa chaperonin family
Heat shock proteins 60kDa
Secondary FlyBase ID(s)
References (5)