FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Complex: WASP AND SCAR HOMOLOG COMPLEX
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General Information
Name
WASP AND SCAR HOMOLOG COMPLEX
Species
D. melanogaster
Symbol
WASH-C
FlyBase ID
FBgg0000508
Date last reviewed
2023-08-08
Number of members
5
Description
Description
The WASP and SCAR Homologue complex (WASH-C) is a multi-subunit complex that activates Arp2/3-mediated actin nucleation. WASH-C contains the nucleation-promoting factor wash, a member of the WASP family. (Adapted from FBrf0232381 and PMID:19922875).
Notes on Group

cpa and cpb have not been included as subunits of the WASP AND SCAR HOMOLOG COMPLEX gene group as they are generally thought to form an independent heterodimeric complex (FBrf0232381).

Source Material
The WASP AND SCAR HOMOLOG COMPLEX Gene Group has been compiled using the following publication(s): Nagel et al., 2017, Verboon et al., 2015, Derivery and Gautreau, 2010, and Jia et al., 2010 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
WASH complex
Related Gene Groups
Other related group(s)
WISKOTT-ALDRICH SYNDROME PROTEINS
Members (5)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
WASH-C
WASP AND SCAR HOMOLOG COMPLEX
SHRC
WASH regulatory complex
WASH core complex
Secondary FlyBase ID(s)
References (5)