FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Complex: SPLICEOSOME COMPLEX C
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General Information
Name
SPLICEOSOME COMPLEX C
Species
D. melanogaster
Symbol
SPL-C-C
FlyBase ID
FBgg0000536
Date last reviewed
2016-09-05
Number of members
91
Description
Description
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex B undergoes a number of structural rearrangements and U4 and U1 snRNPs dissociate to generate complex C, the catalytic spliceosome. (Adapted from PMID:24452469 and PMID:23118483).
Notes on Group

Complex B goes through transition intermediates Bact and B* prior to forming complex C (PMID:24452469 and PMID:23118483). These have not been curated as gene groups.

Source Material
The SPLICEOSOME COMPLEX C Gene Group has been compiled using the following publication(s): Lu and Matera, 2014, Cvitkovic and Jurica, 2013, and Saluz et al., 1988 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
mRNA splicing, via spliceosome
Cellular Component
U2-type catalytic step 2 spliceosome
Related Gene Groups
Parent group(s)
SPLICEOSOME COMPLEX INTERMEDIATES
Members (91)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SPLICEOSOME COMPLEX C
SPL-C-C
SLP-C-C
Secondary FlyBase ID(s)
References (4)